Skip to main content

Does Dihydromyricetin (DHM) Work When Taken the Morning After Drinking?


There are two kinds of supplements which can help with hangovers; supplements taken the same night as drinking and supplements taken the morning after. Dihydromyricetin (DHM) is a supplement that will only work if taken while drinking or immediately after drinking. DHM will NOT work when taken the morning after.

Many people erroneously believe DHM is a “hangover cure”. But to call it a “hangover cure” would imply you had a hangover to begin with. In reality, DHM is a preventative measure. By taking the proper dose during and immediately after drinking, you can prevent yourself from getting a hangover. Once you wake up with a hangover the next morning, the damage has been done, and DHM will not help you.

For those who want to understand why DHM only works as a preventative measure, you need to understand exactly how DHM works.

How Dihydromyricetin Works

Dihydromyricetin has an effect on both a person’s liver and their brain. Scientists have conducted studies in mice which show these effects are able to lower feelings of intoxication, and reduce negative effects associated with alcohol consumption such as hangover symptoms.

The effects DHM has on a person are directly related to alcohol being in their brain and body. If you have not consumed alcohol taking DHM will have no effect.

Dihydromyricetin and the Brain

After you have ingested alcohol and it is running through your blood stream it will inevitably have an effect on your brain. Specifically, alcohol effects two different neurotransmitters. Your feelings, thoughts, emotions, and even muscle movements are effected by neurotransmitters. Think of them as chemical messengers that tell your brain what to do.

Alcohol effects the neurotransmitters GABA and Glutamine. Alcohol binds to GABA receptors in the brain and amplifies the signals it sounds out. The signal GABA sends tells your brain to slow down your heart rate and relax you. When this signal is heavily amplified, you begin to feel “buzzed” and eventually “drunk”. You begin to lose motor control, slur words, and your inhibitions are lowered. When the signal is amplified too much you can pass our completely. People who overdose and die on alcohol have amplified the signal so much their breathing completely stops.

Alcohol also effects Glutamine but in the opposite way. Alcohol reduces the signal your brain receives from Glutamine. Because signals from Glutamine increase brain activity and heart rate, the effect alcohol has on Glutamine also makes you more drunk.

After a long night of heavy drinking, your brain is “tricked” into thinking it is receiving a stronger signal from GABA and a weaker signal from Glutamine. This causes it to produce less GABA and more Glutamine which leads to certain hangover symptoms such as headache, sensitivity to light, anxiety, and trouble getting a full night’s sleep.

Think of it as a “rebound” effect. The alcohol has pulled your brain so far in one direction the night before, your brain rebounds in the other direction the next morning before returning to normal.

Imagine a rubber band being pulled upwards and then let go. The rubber band will dip slightly below its baseline before coming to a complete rest.

DHM binds to GABA receptors in the brain and lessens the effect alcohol has on the GABA neurotransmitter. This reduces the “rebound” effect you experience the next morning which in turn lessens hangover symptoms. It keeps the alcohol from pulling the rubber band as far back as it otherwise would have.

If you take DHM the morning after drinking, the damage has already been done. The rubber band has already been pulled very far back and you are already in the midst of the rebound effect.

Dihydromyricetin and the Liver

Once you consume alcohol, it is processed within your liver. Your liver contains certain enzymes which are responsible for breaking down alcohol into acetaldehyde. At that point a different enzyme breaks down the acetaldehyde into acetic acid. The acetic acid is harmless, but acetaldehyde is not. In fact, acetaldehyde is much more harmful than alcohol itself and is thought to be responsible for many hangover symptoms such as nausea, vomiting, and headaches.

DHM enhances the enzymes in your liver responsible for breaking down both alcohol and acetaldehyde. This helps your body flush both the alcohol and acetaldehyde out of your body before it can do any damage.

While you are sleeping, your body is working hard to break down both alcohol and acetaldehyde. By the time you wake up, the damage has already been done. Taking DHM in the morning might help flush what little acetaldehyde is still in your system out, but the majority of the damage has already been done.

Ensure you take Dihydromyricetin (DHM) while drinking or immediately after

Personally, I believe DHM works best when taken while drinking. I usually take two capsules after every third drink I consume. I believe this not only keeps me from making a complete fool of myself, but it also helps ward of the drowsiness I experience when drinking for long periods of time. The next morning, I wake up with virtually no hangover. If I go crazy I might have a very minor headache, but nothing compared to the crippling hangover I would otherwise experience.

Try Dihydromyricetin Now!


Because DHM works so well, we offer a full money back guarantee on all orders.

Give it a try and see its powerful benefits for yourself.


Subscribe and Save


Save 10% on DHM by enrolling in our subscribe and save program!

Get your DHM automatically delivered each month and save 10% off the usual price.