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How Does Dihydromyricetin (DHM) Protect The Brain?

Many people are aware that regular alcohol consumption has a devastating effect on the liver, but most people aren’t aware it also damages the brain. Alcohol damages the brain by putting it under excess oxidative stress.

Alcohol promotes the generation of reactive oxygen species (ROS), also known as free radicals. Free radicals are small, highly reactive molecules containing an unpaired valance electron and are generated during various metabolic processes. The unpaired electron they contain makes them highly reactive with other substances. Even though small amounts of free radicals are actually good for you, excess amounts can damage and destroy cells in all parts of your body.

“Antioxidants” are substances which can neutralize free radicals by pairing their unpaired valance electron. This makes the free radical unreactive and inhibits its ability to cause further damage to other cells.

Dihydromyricetin is a potent anti-oxidant

Research has shown Dihydromyricetin (DHM) to be an anti-oxidant and help protect the brain from damage caused by excessive alcohol consumption. [1]

An excerpt from the research cited below is as follows:

Ampelopsin(DHM) has previously demonstrated a strong inhibitory effect on H2O2-induced oxidative damage in cell-free systems including red blood cells and in vitro cell cultures. This is due to the scavenging of free radicals by ampelopsin, which reduces radical-induced lipid peroxidation of cell membranes and inhibits MDA generation. Similarly, ampelopsin has been reported to significantly inhibit superoxide anion radical activity and lipid peroxidation of liver homogenate and mitochondria during stimulation of auto-oxidation and induced-oxidation, and the inhibitory effect of ampelopsin on free radicals and lipid peroxidation is concentration-dependent and. Therefore, ampelopsin exhibits favorable antioxidant activity that may mitigate cellular oxidative stress and stimulate the potential of cellular vitality, thus accomplishing the prevention of neurodegenerative diseases, cardiovascular diseases, cancer and other diseases.”

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Even if you don't get bad hangovers, DHM's ability to reduce liver and brain damage due to alcohol makes using it a smart choice for every drinker.

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Cited Studies

  1. Pharmacological potential of ampelopsin in Rattan tea - ScienceDirect

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