Dihydromyricetin (DHM) is a natural extract of the Oriental Raisin Tree. (Hovenia Dulcis) DHM has been used for centuries in traditional Chinese medicine as a hangover cure and intoxication blocker, but has just recently been the subject of focused research.
Initial studies concluded that DHM supplements greatly reduces hangover symptoms and negates many of the negative side effects commonly associated with drunkenness such as slurred speech, loss of coordination, and lowered reaction time without any adverse side effects.
Our Dihydromyricetin (DHM) is manufactured in the United States and rigorously tested for purity and safety.
Skeptical about DHM’s effectiveness or not sure if it’s right for you? Give it a try by ordering a sample pack.
If you aren’t satisfied with it’s effects, just let us know and we will provide you with a full refund!
This stuff really works. Either before you imbibe, or after. If you have had too much to drink, it will stop the spins, and staggers, and you don't get a hangover the next morning. It will knock out an existing hangover as well. I have problems with some of my younger workers showing up in the morning having partied all night, and they are almost useless. A dose of this and they are back in shape to work.Bruce
I tried it before drinking once and it was like I was drinking non-alcoholic beer, I wasn't even phased. I take it at the end of a long night of partying on a weeknight and am up for work at 7 and even feel more tired than hungover at all. It also does well to take mid-drinking in order to keep from getting out of line. I've never experienced such a strange effect like this has over alcohol, you should have some on the shelf behind every bar!Jen
This was a great product and performs exactly as advertised. Drinks on me!Matt
A new dietary supplement is becoming more popular by the day. It promises to be the single best hangover cure available on the market. It is completely safe and there are no side effects. Some have dubbed Dihydromyricetin (DHM) to be the “Antidote to alcohol” because of its ability to prevent hangovers, feelings of intoxication, and certain alcohol withdrawal symptoms.
Dihydromyricetin is a natural extract of the hovenia dulcis tree, which is native to China and Korea. Hovenia dulcis has long been used in traditional Chinese medicine to prevent hangovers and reverse alcohol intoxication. In 2007, hovenia dulcis became the subject of focused research, where scientists determined the active ingredient in hovenia dulcis responsible for its anti-alcohol effects was Dihydromyricetin.
Researchers were first interested in DHM's potential as a treatment for alcoholism, but quickly discovered its usefulness in preventing hangovers, increasing the rate at which someone who's intoxicated sobers up, and protecting the liver and brain from damage caused by alcohol.
The first study showing DHM's potential involved researchers giving copious amounts of alcohol to rats. The researchers split the rats up into two groups; “Group A” and “Group DHM”. Researchers injected Group A with the “human equivalent” of 15-20 beers in two hours. These rats lost their ability to stand and immediately rolled onto their backs. It took the rats in “Group A” nearly 70 minutes to stand back up on average.
The rats in “Group DHM” were injected with the same amount of alcohol, but they were also given an injection of 1ml pure Dihydromyricetin. These rats also rolled over onto their backs almost immediately. However, these rats were able to stand up in only five minutes! This means the rats in “Group DHM” stood up 14 times faster than the rats in “Group A”.
Scientists also tested DHM on drunk rats in mazes. Rats given large amounts of alcohol cowered in corners and didn’t explore the maze they were placed in. On the other hand, rats also given the DHM extract acted similarly to sober mice. They explored the maze instead of hiding in one spot. 
Finally, scientists studied DHM’s ability to reduce alcohol cravings in rats.
The rats were broken up into two groups. Let’s call these groups “Group A” and “Group DHM” Both groups were given two different drinking options for ten straight weeks. “Group A” was given a choice between sugar water and sugar water mixed with alcohol. “Group DHM” was given a choice between sugar water and sugar water mixed alcohol and laced with DHM.
The rats in “Group A” became increasingly addicted to the alcohol over the ten week period. They consumed larger amounts of alcohol as the experiment continued. The rats in “Group DHM” drank less alcohol as the experiment continued. By the end of the experiment, rats in “Group DHM” drank only 1/4th the amount of alcohol compared to rats in “Group A”. 
Similar studies have since been performed on humans, and have found DHM to be just as safe and effective when used by people. Dihydromyricetin has not only been identified as possibly the only candidate for treating alcoholism that doesn't have any side effects , but also that it is completely safe even at over ten times the recommended dose.
Dihydromyricetin has a very unique mechanism of action in that it works on both the brain and liver. This produces complimentary effects which combine to produce its powerful benefts. To understand how it works, one must first understand how alcohol effects the body and brain.
After you ingest alcohol, it quickly enters your digestive tract and is absorbed into your blood. That blood makes its way to your liver, where an enzyme called alcohol dehydrogenase (ADH) metabolizes the alcohol. However, your liver metabolizes alcohol at a constant rate, regardless of how much alcohol you consume.
On average a single 1.5oz shot of 35% alcohol or a 12oz 4% beer can be fully metabolized in one hour. When you consume alcohol faster than your liver can metabolize it, alcohol builds up in your blood stream. Your blood alcohol content (BAC) rises, and alcohol has pervasive effects on your brain.
When alcohol reaches your brain it affects two different neurotransmitters. Simply put, neurotransmitters are chemicals your brain cells use to control emotions, movement, behavior, and thought processes. Two categories of neurotransmitters are inhibitory and exhibitory. Inhibitory neurotransmitters have a calming effect and “slow” things down. Exhibitory neurotransmitters increase energy levels and brain activity.
One neurotransmitter affected by alcohol is GABA. Alcohol binds to GABA receptors in the brain and amplifies its effect. As the brain receives a stronger message from GABA, you begin to feel calm, and your heart rate slows down.
When you continue to drink, GABA signals are amplified more and more. Eventually, you experience loss of motor control, inhibitions are lowered, and speech begins to slur. When alcohol in consumed at a dangerous level, breathing and heart rate can slow to the point you experience coma or death.
Dihydromyricetin binds to GABA receptors in the brain and blocks the effect alcohol has on GABA receptors.  Theoretically, this should reduce certain feelings related to intoxication as alcohol is only amplifying the exhibitory neurotransmitter Glutamate (another neurotransmitter effected by alcohol). This theory was put to the test, and has held up in various studies. 
When Dihydromyricetin is taken before drinking, alcohol can’t amplify GABA and you don’t feel as intoxicated. When DHM is taken after drinking, it can accelerate the rate at which one sobers up. DHM’s benefit in the brain isn’t just limited to GABA receptors. DHM is a potent antioxidant able to prevent damage done by alcohol to dendrites. 
Earlier I mentioned alcohol is metabolized at a constant rate in your liver by the enzyme ADH. Any alcohol which isn’t able to be processed by ADH backs up, circulates through your bloodstream, and makes you drunk.
Dihydromyricetin enhances the ADH enzyme, speeding up the liver’s ability to metabolize alcohol. . This means not only does DHM block alcohol’s effect on GABA, but it also helps flush alcohol out of your system. It also has the same effect on the enzyme which metabolizes acetaldehyde (ALDH).  Acetaldehyde is an extremely toxic byproduct formed when alcohol is metabolized in the liver. Acetaldehyde toxicity is one of the main causes of hangovers.
The faster your liver can metabolize alcohol and acetaldehyde, the faster it can resume its normal duties. This results in decreased damage done by alcohol to the liver. This assertion has been proven true in many studies, on which more information is available here.
If you enjoy drinking but get frustrated with the negative side effects of alcohol use, Dihydromyricetin will completely change your relationship with alcohol. All it takes is one or two Dihydromyricetin pills after a night of drinking to eliminate almost every negative hangover symptom. The only hangover cause DHM won't affect is dehydration, which actually plays a much smaller role in hangovers than most people believe. (Acetaldehyde is the main culprit, and just 2 glasses of water before bed is plenty to rehydrate.)
If you are concerned about the negative health effects of drinking, Dihydromyricetin can give you peace of mind. Research has proven that it can prevent much of the damage caused by alcohol to both the liver, and the brain.
We enjoy using alcohol ourselves, and started this business after realizing how much more enjoyable DHM makes the next morning. The overwhlemingly positive experiences of our customers, the volumes of research, and our own personal experiences (we never drink without it), have convinced us that DHM is an essential supplement for any drinker.
We're fully committed to bringing you only the purest, highest quality Dihydromyricetin. For that reason, our product is manufactured in the United States at a facility which is regularly inspected by the FDA and complies with all safety regulations. Many supplement companies claim that their product is pure and free of contaminants, but we prove this by making our Certificate of Analysis publically available.
We know you'll be more than satisfied with Dihydromyricetin's ability to prevent hangovers and reverse intoxication, which is why we provide a complete money back guarantee. If you aren't happy with our DHM, let us know and we will give you a full refund, no questions asked.